Wednesday, 13 April 2011

Life Cycles of Influenza

I focussed on finding images of Influenza life cycles to try and explain what happens at each stage so that I am more aware of where to begin with script and drawings

"Receptor-bound viruses are taken into the cell by endocytosis. In the low pH environment of the endosome, RNP is released from MP1, and the viral lipoprotein envelope fuses with the lipid-bilayer of the vesicle, releasing viral RNP into the cell cytoplasm, from where it is transported into the nucleus. New viral proteins are translated from transcribed messenger RNA (mRNA). New viral RNA is encased in the capsid protein, and together with new matrix protein is then transported to sites at the cell surface where envelope haemagglutinin and neuraminadase components have been incorporated into the cell membrane. Progeny virions are formed and released by budding.

The cell does not die (at least not initially). "

From this information I know the rough structure of the acts, which are:

Act 1 - Virus flows through bloodstream and attaches itself to nearest cell (I dont know at this stage if I want the virus to float through air first and then enter a human body to show how it is caught)

Act 2 - Virus fuses with cells cytoplasm and release viral RNP to effect the nucleus and translated to RNA where it becomes encased in capsid protein and transported to cell surface

Act 3 - The production of Progeny virons and released into bloodstream through budding process (four or five to make point that the virus multiples)


  1. Hey there Adam, good to see your research. One thing you need to consider is your target audience and the most appropriate way to convey your story.

  2. yep started to think about that will be uploaded soon not sure on audience yet though?